The year is 521 A.D. and Lesser Blackthroat, assassin for a secret sect of the Catholic Church, attempts to obtain the blood of a messiah in hopes of washing clean his cursed spirit. His journey leads him to an underground cathedral in Mesopotamia where the ancient undead guard Blackthroat's prize and the secret to pure immortality.

The year is 2005 A.D. and after 500 years, Marco Esperanza's wait for revenge ends when he finally confronts the man on whom he blames his fate, Lesser Blackthroat. However, Marco learns that nothing is as it seems when he is confronted by a shadow from his past.